藥品參考
Nifurtimox
Nifurtimox is a medicine in the class anti parasitic.
- 藥物類別: Anti Parasitic
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Parasitic
- 常見劑型
- 錠劑
- 商品名
- 1
- 國家與市場
- 1
作用方式
Mechanism not fully understood. Nifurtimox is activated by type I and type II nitroreductases, producing toxic intermediate metabolites and/or reactive oxygen species that induce DNA damage and cell death of intracellular and extracellular T. cruzi.
懷孕與哺乳
- 懷孕
- Unsafe May cause fetal harm based on animal studies; treatment of chronic Chagas disease in pregnancy not recommended; acute symptomatic disease requires case-by-case risk-benefit evaluation.
- 哺乳
- Unknown Nifurtimox is present in breast milk (estimated infant dose less than 15% of the pediatric daily dose); monitor infants for vomiting, rash, decreased appetite, pyrexia and irritability; weigh benefits of breastfeeding against maternal need.
已通報的副作用
- Vomiting
- Abdominal pain
- Headache
- Decreased appetite
- Nausea
- Pyrexia
禁忌症
- Known hypersensitivity to nifurtimox or any excipients
- Alcohol consumption during treatment
哪些人需要特別留意
- Genotoxicity demonstrated in humans, in vitro and in rodents; carcinogenicity in humans unknown.
- Embryo-fetal toxicity: can cause fetal harm; pregnancy test before treatment; effective contraception during treatment and for 6 months after; males use condoms during and for 3 months after.
- May worsen neurological and psychiatric conditions (brain injury, seizures, psychiatric disease); use under close medical supervision.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Nifurtimox 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Nifurtimox used for?
Nifurtimox is a medicine in the class anti parasitic.
What side effects have been reported with Nifurtimox?
Vomiting, Abdominal pain, Headache, Decreased appetite, Nausea, Pyrexia.
Can Nifurtimox be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause fetal harm based on animal studies; treatment of chronic Chagas disease in pregnancy not recommended; acute symptomatic disease requires case-by-case risk-benefit evaluation. Breastfeeding: Unknown. Nifurtimox is present in breast milk (estimated infant dose less than 15% of the pediatric daily dose); monitor infants for vomiting, rash, decreased appetite, pyrexia and irritability; weigh benefits of breastfeeding against maternal need.
What does Nifurtimox interact with?
MediHelp does not list a checked interaction for Nifurtimox yet. Always tell your pharmacist about every medicine you take.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
