藥品參考
Secnidazole
Secnidazole is a medicine in the class anti parasitic. It is used for bacterial vaginosis.
- 藥物類別: Anti Parasitic
- 用途: bacterial vaginosis
最後更新
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Parasitic
- 常見劑型
- 錠劑, 散劑包
- 常見規格
- 500 mg, 1 g, 2 g/4.8 g
- 已知交互作用
- 1 (中度: 1)
- 商品名
- 13
- 國家與市場
- 4
用途
作用方式
Secnidazole is a nitroimidazole derivative; 5-nitroimidazoles enters the bacterial cell as an inactive prodrug where the nitro group is reduced by bacterial enzymes to radical anions. It is believed that these radical anions interfere with bacterial DNA synthesis of susceptible isolates
成人常用劑量（仿單摘要）
Bacterial Vaginosis: 1 packet (2 grams) of granules or tablet PO once as a single dose, without regard to timing of meals
懷孕與哺乳
- 懷孕
- Unknown Limited human data; no harm in rats or rabbits at up to 4 times the clinical dose. A nitroimidazole like metronidazole, which has far more pregnancy data and is preferred for bacterial vaginosis or trichomonas in pregnancy.
- 哺乳
- Unknown No human milk data; related drugs pass into milk. US label: breastfeeding not recommended during treatment and for 96 hours after the single dose (possible tumour risk in animals); pump and discard. LactMed: vaginal treatments give lower milk levels. e-lactancia: compatible.
已通報的副作用
- Headache
- Vomiting
- Diarrhea
- Nausea
- Vulvovaginal candidiasis
- Dysgeusia
禁忌症
- Hypersensitivity to secnidazole, excipients of the formulation, or other nitroimidazole derivatives
- Patients with Cockayne syndrome
哪些人需要特別留意
- Severe irreversible hepatotoxicity/acute liver failure with fatal outcomes reported after initiation of metronidazole in patients with Cockayne syndrome
- Carcinogenicity has been seen in mice and rats treated long term with nitroimidazole derivatives, which are structurally related to secnidazole; avoid long-term use
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (1)
- Ethanol + Secnidazole Moderate
同類別的其他藥品
常見問題
What is Secnidazole used for?
Secnidazole is a medicine in the class anti parasitic. It is used for Bacterial vaginosis, Trichomoniasis.
What side effects have been reported with Secnidazole?
Headache, Vomiting, Diarrhea, Nausea, Vulvovaginal candidiasis, Dysgeusia.
Can Secnidazole be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data; no harm in rats or rabbits at up to 4 times the clinical dose. A nitroimidazole like metronidazole, which has far more pregnancy data and is preferred for bacterial vaginosis or trichomonas in pregnancy. Breastfeeding: Unknown. No human milk data; related drugs pass into milk. US label: breastfeeding not recommended during treatment and for 96 hours after the single dose (possible tumour risk in animals); pump and discard. LactMed: vaginal treatments give lower milk levels. e-lactancia: compatible.
What does Secnidazole interact with?
MediHelp lists 1 known interactions for Secnidazole. Moderate: 1. The most serious include Ethanol.
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