藥品參考
Mesalamine
Mesalamine is a medicine in the class gastrointestinal tract. It is used for ulcerative colitis.
- 藥物類別: Gastrointestinal Tract
- 用途: ulcerative colitis
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Gastrointestinal Tract
- 又稱
- Mesalazine
- 常見劑型
- 錠劑, 膠囊, 栓劑, 散劑包, 口服懸液
- 常見規格
- 1 g, 500 mg, 2 g
- 已知交互作用
- 125 (嚴重: 2 · 中度: 48 · 輕微: 75)
- 商品名
- 50
- 國家與市場
- 5
用途
作用方式
Anti-inflammatory agent; mesalamine (5-aminosalicylic acid) is the active component of sulfasalazine, but specific MOA is unknown; probably inhibits prostaglandin and leukotriene synthesis and release in colon.
成人常用劑量（仿單摘要）
Ulcerative Colitis (Pentasa): 1 g/day orally four times daily for up to 8 weeks.
懷孕與哺乳
- 懷孕
- Safe Meta-analyses and cohort studies show no reliable link with birth defects, miscarriage or poor outcomes; no harm in animals. Active ulcerative colitis itself raises pregnancy risks, so continue treatment.
- 哺乳
- Safe Passes into milk in small amounts (mesalamine 0.1% or less of the maternal dose; more of an inactive metabolite). A few infants had diarrhoea. LactMed: not a reason to stop breastfeeding; watch the infant for diarrhoea.
已通報的副作用
- Headache
- Abdominal pain
- Flatulence
- GI discomfort
禁忌症
- Hypersensitivity to mesalamine or salicylates
- Breastfeeding
- Rectal suspension: Hypersensitivity to salicylates, aminosalicylates or to any ingredients in the suppository vehicle
哪些人需要特別留意
- Oligospermia has been reported in males.
- ensure adequate fluid intake during treatment; evaluate renal function prior to initiation of therapy and periodically while on therapy.
- advise patients to avoid sun exposure, wear protective clothing, and use a broad-spectrum sunscreen when outdoors.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (125)
- Measles mumps rubella and varicella vaccine live + Mesalamine Major
- Mesalamine + Varicella virus vaccine live Major
- Aceclofenac + Mesalamine Moderate
- Acemetacin + Mesalamine Moderate
- Acetylsalicylic acid + Mesalamine Moderate
- Aspirin + Mesalamine Moderate
- Aspirin / citric acid / sodium bicarbonate + Mesalamine Moderate
- Aspirin rectal + Mesalamine Moderate
- Azathioprine + Mesalamine Moderate
- Balsalazide + Mesalamine Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Mesalamine 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
在網頁版免費試用 Pro+ 7 天，無需信用卡。
同類別的其他藥品
常見問題
What is Mesalamine used for?
Mesalamine is a medicine in the class gastrointestinal tract. It is used for Ulcerative colitis.
What side effects have been reported with Mesalamine?
Headache, Abdominal pain, Flatulence, GI discomfort.
Can Mesalamine be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Meta-analyses and cohort studies show no reliable link with birth defects, miscarriage or poor outcomes; no harm in animals. Active ulcerative colitis itself raises pregnancy risks, so continue treatment. Breastfeeding: Safe. Passes into milk in small amounts (mesalamine 0.1% or less of the maternal dose; more of an inactive metabolite). A few infants had diarrhoea. LactMed: not a reason to stop breastfeeding; watch the infant for diarrhoea.
What does Mesalamine interact with?
MediHelp lists 125 known interactions for Mesalamine. Major: 2 · Moderate: 48 · Minor: 75. The most serious include Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac.
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