藥品參考
Paricalcitol
Paricalcitol is a medicine in the class musculoskeletal. It is used for hyperparathyroidism.
- 藥物類別: Musculoskeletal
- 用途: hyperparathyroidism
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Musculoskeletal
- 常見劑型
- 膠囊, 注射劑
- 已知交互作用
- 17 (中度: 6 · 輕微: 11)
- 商品名
- 1
- 國家與市場
- 1
用途
作用方式
Synthetic vitamin D2 analog that binds the vitamin D receptor (VDR), selectively activating vitamin D responsive pathways; reduces PTH levels by inhibiting PTH synthesis and secretion.
成人常用劑量（仿單摘要）
Secondary hyperparathyroidism in CKD on dialysis: initial 0.04 mcg/kg to 0.1 mcg/kg (2.8 mcg to 7 mcg) IV bolus, no more frequently than every other day, any time during dialysis
懷孕與哺乳
- 懷孕
- Unknown Limited human data are insufficient to inform risk; animal studies showed slightly increased embryofetal loss at maternally toxic doses.
- 哺乳
- Unknown No human milk data; present in rat milk. Monitor breastfed infants for hypercalcemia and weigh benefits of breastfeeding against maternal need.
已通報的副作用
- Nausea
- Vomiting
- Edema
- Gastrointestinal hemorrhage
- Chills
- Pyrexia
禁忌症
- Hypercalcemia
- Vitamin D toxicity
- Known hypersensitivity to paricalcitol or any inactive ingredient (angioedema and urticaria reported)
哪些人需要特別留意
- Hypercalcemia can cause cardiac arrhythmias and seizures; risk increased with high-dose calcium, thiazides or vitamin D compounds. Monitor serum calcium; reduce dose or discontinue if it occurs.
- Digitalis toxicity risk increases with hypercalcemia; monitor calcium and patients on digitalis.
- Adynamic bone disease with increased fracture risk may develop if intact PTH is oversuppressed; monitor PTH.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (17)
- Carbamazepine + Paricalcitol Moderate
- Cholestyramine + Paricalcitol Moderate
- Clarithromycin + Paricalcitol Moderate
- Digoxin + Paricalcitol Moderate
- Ketoconazole + Paricalcitol Moderate
- Paricalcitol + Posaconazole Moderate
- Apalutamide + Paricalcitol Minor
- Bosentan + Paricalcitol Minor
- Chloramphenicol + Paricalcitol Minor
- Colesevelam + Paricalcitol Minor
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Paricalcitol 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Paricalcitol used for?
Paricalcitol is a medicine in the class musculoskeletal. It is used for Hyperparathyroidism.
What side effects have been reported with Paricalcitol?
Nausea, Vomiting, Edema, Gastrointestinal hemorrhage, Chills, Pyrexia.
Can Paricalcitol be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data are insufficient to inform risk; animal studies showed slightly increased embryofetal loss at maternally toxic doses. Breastfeeding: Unknown. No human milk data; present in rat milk. Monitor breastfed infants for hypercalcemia and weigh benefits of breastfeeding against maternal need.
What does Paricalcitol interact with?
MediHelp lists 17 known interactions for Paricalcitol. Moderate: 6 · Minor: 11. The most serious include Carbamazepine, Cholestyramine, Clarithromycin.
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