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藥物交互作用

Apalutamide + Paricalcitol

嚴重程度: 輕微

Apalutamide and Paricalcitol: minor interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Apalutamide may modestly reduce paricalcitol exposure. The clinical effect is likely small and detectable through routine PTH monitoring.

用白話說明這項交互作用的意義

Apalutamide and Paricalcitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Apalutamide belongs to Endocrine; Paricalcitol belongs to Musculoskeletal.

證據等級: Low

為什麼會發生

Apalutamide induces CYP3A4, which contributes to paricalcitol metabolism.

處置方式

Monitor intact PTH, calcium and phosphorus and adjust the paricalcitol dose as needed.

可向藥師詢問的問題

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Apalutamide 與 Paricalcitol 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

在網頁版免費試用 Pro+ 14 天,無需信用卡。

常見問題

Can I take Apalutamide with Paricalcitol?

MediHelp rates the interaction as minor. Apalutamide and Paricalcitol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Apalutamide may modestly reduce paricalcitol exposure. The clinical effect is likely small and detectable through routine PTH monitoring.

How serious is the interaction between Apalutamide and Paricalcitol?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor intact PTH, calcium and phosphorus and adjust the paricalcitol dose as needed.

What other medicines interact with Apalutamide?

MediHelp also lists interactions of Apalutamide with, for example, Cabotegravir, Cobicistat, Doravirine. The full list is on the Apalutamide page.

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