藥物交互作用
Carbamazepine + Paricalcitol
嚴重程度: 中度
Carbamazepine and Paricalcitol: moderate interaction.
最後更新
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摘要
Carbamazepine may reduce paricalcitol exposure and weaken parathyroid hormone suppression. Anticonvulsant enzyme inducers also contribute to vitamin D deficiency and bone loss.
用白話說明這項交互作用的意義
Carbamazepine and Paricalcitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbamazepine belongs to Central Nervous System; Paricalcitol belongs to Musculoskeletal.
為什麼會發生
Carbamazepine induces CYP3A4, increasing paricalcitol metabolism.
處置方式
Monitor PTH, calcium and phosphate and adjust the paricalcitol dose as required. Recheck if carbamazepine is changed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Carbamazepine 的其他交互作用
Paricalcitol 的其他交互作用
常見問題
Can I take Carbamazepine with Paricalcitol?
MediHelp rates the interaction as moderate. Carbamazepine and Paricalcitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbamazepine may reduce paricalcitol exposure and weaken parathyroid hormone suppression. Anticonvulsant enzyme inducers also contribute to vitamin D deficiency and bone loss.
How serious is the interaction between Carbamazepine and Paricalcitol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor PTH, calcium and phosphate and adjust the paricalcitol dose as required. Recheck if carbamazepine is changed.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
