藥物交互作用
Abacavir + Nevirapine
嚴重程度: 輕微
Abacavir and Nevirapine: minor interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Nevirapine and abacavir are commonly used together in HIV regimens and no pharmacokinetic interaction is of concern. Both may be followed by immune reconstitution inflammatory syndrome when therapy starts, but this is a feature of antiretroviral initiation rather than a drug interaction. Both drugs can cause hypersensitivity reactions, which can be confused clinically.
用白話說明這項交互作用的意義
Abacavir and Nevirapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Abacavir belongs to Anti Virals; Nevirapine belongs to Anti Virals.
為什麼會發生
No established interaction; immune recovery after antiretroviral initiation causes IRIS, and both drugs carry hypersensitivity risk.
處置方式
Monitor for inflammatory symptoms and rash or fever during the first weeks of therapy. Confirm HLA-B*5701 status before abacavir use.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Nevirapine 的其他交互作用
Abacavir 的其他交互作用
常見問題
Can I take Abacavir with Nevirapine?
MediHelp rates the interaction as minor. Abacavir and Nevirapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nevirapine and abacavir are commonly used together in HIV regimens and no pharmacokinetic interaction is of concern. Both may be followed by immune reconstitution inflammatory syndrome when therapy starts, but this is a feature of antiretroviral initiation rather than a drug interaction. Both drugs can cause hypersensitivity reactions, which can be confused clinically.
How serious is the interaction between Abacavir and Nevirapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for inflammatory symptoms and rash or fever during the first weeks of therapy. Confirm HLA-B*5701 status before abacavir use.
What other medicines interact with Nevirapine?
MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, Ranolazine, St john's wort. The full list is on the Nevirapine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
