藥物交互作用
Abacavir + Methadone
嚴重程度: 輕微
Abacavir and Methadone: minor interaction.
最後更新
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摘要
Abacavir may modestly increase methadone clearance, which could occasionally lead to reduced opioid effect or withdrawal symptoms. In studies the changes in methadone exposure were small and dose adjustment was generally not needed.
用白話說明這項交互作用的意義
Abacavir and Methadone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Abacavir belongs to Anti Virals; Methadone belongs to Musculoskeletal.
為什麼會發生
Possible modest increase in methadone clearance; the exact mechanism is not established.
處置方式
Monitor for withdrawal symptoms or reduced effect after starting abacavir and increase the methadone dose only if clinically needed.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Methadone 的其他交互作用
Abacavir 的其他交互作用
常見問題
Can I take Abacavir with Methadone?
MediHelp rates the interaction as minor. Abacavir and Methadone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Abacavir may modestly increase methadone clearance, which could occasionally lead to reduced opioid effect or withdrawal symptoms. In studies the changes in methadone exposure were small and dose adjustment was generally not needed.
How serious is the interaction between Abacavir and Methadone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for withdrawal symptoms or reduced effect after starting abacavir and increase the methadone dose only if clinically needed.
What other medicines interact with Methadone?
MediHelp also lists interactions of Methadone with, for example, Alvimopan, Calcium / magnesium / potassium / sodium oxybates, Droperidol. The full list is on the Methadone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
