藥物交互作用
Abiraterone + Cannabidiol
嚴重程度: 中度
Abiraterone and Cannabidiol: moderate interaction.
最後更新
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摘要
Abiraterone may inhibit CYP2C19 and raise cannabidiol exposure, increasing sedation, somnolence and liver enzyme elevations. The effect is predicted from mechanism.
用白話說明這項交互作用的意義
Abiraterone and Cannabidiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Abiraterone belongs to Endocrine; Cannabidiol belongs to Central Nervous System.
為什麼會發生
Abiraterone inhibits CYP2C19, reducing cannabidiol metabolism.
處置方式
Monitor for sedation and adverse effects and liver enzymes; reduce cannabidiol dose if adverse effects occur.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Abiraterone 的其他交互作用
Cannabidiol 的其他交互作用
常見問題
Can I take Abiraterone with Cannabidiol?
MediHelp rates the interaction as moderate. Abiraterone and Cannabidiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Abiraterone may inhibit CYP2C19 and raise cannabidiol exposure, increasing sedation, somnolence and liver enzyme elevations. The effect is predicted from mechanism.
How serious is the interaction between Abiraterone and Cannabidiol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation and adverse effects and liver enzymes; reduce cannabidiol dose if adverse effects occur.
What other medicines interact with Abiraterone?
MediHelp also lists interactions of Abiraterone with, for example, Radium-223 dichloride, Thioridazine, Amobarbital. The full list is on the Abiraterone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
