藥物交互作用
Abobotulinumtoxina + Atropine
嚴重程度: 中度
Abobotulinumtoxina and Atropine: moderate interaction.
最後更新
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摘要
Anticholinergic drugs such as atropine may add to the effects of botulinum toxin, which blocks acetylcholine release. This can increase systemic anticholinergic effects such as dry mouth, blurred vision and urinary retention, and may increase muscle weakness.
用白話說明這項交互作用的意義
Abobotulinumtoxina and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive anticholinergic effects at cholinergic synapses combined with presynaptic blockade of acetylcholine release by the toxin.
處置方式
Monitor for excessive weakness, swallowing or breathing difficulty and anticholinergic symptoms after injection. Avoid unnecessary additional anticholinergics around the time of treatment.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Atropine 的其他交互作用
常見問題
Can I take Abobotulinumtoxina with Atropine?
MediHelp rates the interaction as moderate. Abobotulinumtoxina and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anticholinergic drugs such as atropine may add to the effects of botulinum toxin, which blocks acetylcholine release. This can increase systemic anticholinergic effects such as dry mouth, blurred vision and urinary retention, and may increase muscle weakness.
How serious is the interaction between Abobotulinumtoxina and Atropine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive weakness, swallowing or breathing difficulty and anticholinergic symptoms after injection. Avoid unnecessary additional anticholinergics around the time of treatment.
What other medicines interact with Atropine?
MediHelp also lists interactions of Atropine with, for example, Eluxadoline, Henbane, Pramlintide. The full list is on the Atropine page.
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