藥物交互作用
Amantadine + Atropine
嚴重程度: 中度
Amantadine and Atropine: moderate interaction.
最後更新
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摘要
Amantadine has anticholinergic properties, and atropine is a potent antimuscarinic. Together they may increase dry mouth, blurred vision, constipation, urinary retention, tachycardia and confusion, particularly in older adults.
用白話說明這項交互作用的意義
Amantadine and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amantadine belongs to Anti Virals; Atropine belongs to Miscellaneous.
為什麼會發生
Additive anticholinergic effects (pharmacodynamic).
處置方式
Monitor for anticholinergic effects and mental status changes, especially in elderly patients. Reduce the dose of one agent if adverse effects develop.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amantadine 的其他交互作用
Atropine 的其他交互作用
常見問題
Can I take Amantadine with Atropine?
MediHelp rates the interaction as moderate. Amantadine and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amantadine has anticholinergic properties, and atropine is a potent antimuscarinic. Together they may increase dry mouth, blurred vision, constipation, urinary retention, tachycardia and confusion, particularly in older adults.
How serious is the interaction between Amantadine and Atropine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects and mental status changes, especially in elderly patients. Reduce the dose of one agent if adverse effects develop.
What other medicines interact with Amantadine?
MediHelp also lists interactions of Amantadine with, for example, Ethanol, Memantine-donepezil, Metoclopramide. The full list is on the Amantadine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
