藥物交互作用
Aceclofenac + Mesalamine
嚴重程度: 中度
Aceclofenac and Mesalamine: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Mesalamine can cause interstitial nephritis, and NSAIDs reduce renal prostaglandin-mediated perfusion. Together they may raise the risk of kidney injury.
用白話說明這項交互作用的意義
Aceclofenac and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aceclofenac belongs to Musculoskeletal; Mesalamine belongs to Gastrointestinal Tract.
為什麼會發生
Additive nephrotoxicity from mesalamine interstitial nephritis and NSAID-induced renal hemodynamic effects.
處置方式
Monitor serum creatinine at baseline and periodically; avoid NSAIDs where possible in patients with renal impairment.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Mesalamine 的其他交互作用
Aceclofenac 的其他交互作用
常見問題
Can I take Aceclofenac with Mesalamine?
MediHelp rates the interaction as moderate. Aceclofenac and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mesalamine can cause interstitial nephritis, and NSAIDs reduce renal prostaglandin-mediated perfusion. Together they may raise the risk of kidney injury.
How serious is the interaction between Aceclofenac and Mesalamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine at baseline and periodically; avoid NSAIDs where possible in patients with renal impairment.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Acemetacin. The full list is on the Mesalamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
