藥物交互作用
Acetylsalicylic acid + Mesalamine
嚴重程度: 中度
Acetylsalicylic acid and Mesalamine: moderate interaction.
最後更新
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摘要
Mesalamine is a salicylate with potential for renal toxicity, and combining it with aspirin or other NSAIDs may add to the risk of kidney injury. The risk is mainly with higher aspirin doses or pre-existing renal impairment.
用白話說明這項交互作用的意義
Acetylsalicylic acid and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Acetylsalicylic acid belongs to Musculoskeletal; Mesalamine belongs to Gastrointestinal Tract.
為什麼會發生
Additive effects on renal prostaglandin-dependent perfusion and possible direct tubulointerstitial toxicity of salicylates.
處置方式
Monitor serum creatinine and urinalysis periodically, particularly with higher-dose aspirin or renal impairment. Avoid unnecessary additional NSAIDs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Acetylsalicylic acid 的其他交互作用
Mesalamine 的其他交互作用
常見問題
Can I take Acetylsalicylic acid with Mesalamine?
MediHelp rates the interaction as moderate. Acetylsalicylic acid and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mesalamine is a salicylate with potential for renal toxicity, and combining it with aspirin or other NSAIDs may add to the risk of kidney injury. The risk is mainly with higher aspirin doses or pre-existing renal impairment.
How serious is the interaction between Acetylsalicylic acid and Mesalamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urinalysis periodically, particularly with higher-dose aspirin or renal impairment. Avoid unnecessary additional NSAIDs.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
