藥物交互作用
Aspirin / citric acid / sodium bicarbonate + Mesalamine
嚴重程度: 中度
Aspirin / citric acid / sodium bicarbonate and Mesalamine: moderate interaction.
最後更新
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摘要
Mesalamine can rarely cause interstitial nephritis and the aspirin in this effervescent analgesic can reduce renal prostaglandin-dependent perfusion. Together they may increase the risk of kidney injury.
用白話說明這項交互作用的意義
Aspirin / citric acid / sodium bicarbonate and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive nephrotoxicity through salicylate-related renal effects and mesalamine-related interstitial nephritis.
處置方式
Monitor serum creatinine periodically, especially with frequent aspirin use or renal impairment; prefer paracetamol for analgesia if possible.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Mesalamine 的其他交互作用
常見問題
Can I take Aspirin / citric acid / sodium bicarbonate with Mesalamine?
MediHelp rates the interaction as moderate. Aspirin / citric acid / sodium bicarbonate and Mesalamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mesalamine can rarely cause interstitial nephritis and the aspirin in this effervescent analgesic can reduce renal prostaglandin-dependent perfusion. Together they may increase the risk of kidney injury.
How serious is the interaction between Aspirin / citric acid / sodium bicarbonate and Mesalamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine periodically, especially with frequent aspirin use or renal impairment; prefer paracetamol for analgesia if possible.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Mesalamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
