藥物交互作用
Acetylsalicylic acid + Hydrocortisone
嚴重程度: 中度
Acetylsalicylic acid and Hydrocortisone: moderate interaction.
最後更新
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摘要
Systemic corticosteroids combined with aspirin increase the risk of gastric ulceration and gastrointestinal bleeding. Corticosteroids may also lower salicylate levels, which can rise when the steroid is withdrawn.
用白話說明這項交互作用的意義
Acetylsalicylic acid and Hydrocortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Acetylsalicylic acid belongs to Musculoskeletal; Hydrocortisone belongs to Endocrine.
為什麼會發生
Additive gastric mucosal injury, plus corticosteroid-induced increase in salicylate clearance.
處置方式
Consider a proton pump inhibitor in patients with ulcer risk factors. Monitor for GI bleeding and for salicylate toxicity when steroids are tapered at high aspirin doses.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Acetylsalicylic acid 的其他交互作用
Hydrocortisone 的其他交互作用
常見問題
Can I take Acetylsalicylic acid with Hydrocortisone?
MediHelp rates the interaction as moderate. Acetylsalicylic acid and Hydrocortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids combined with aspirin increase the risk of gastric ulceration and gastrointestinal bleeding. Corticosteroids may also lower salicylate levels, which can rise when the steroid is withdrawn.
How serious is the interaction between Acetylsalicylic acid and Hydrocortisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider a proton pump inhibitor in patients with ulcer risk factors. Monitor for GI bleeding and for salicylate toxicity when steroids are tapered at high aspirin doses.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
