藥物交互作用
Aclidinium + Trihexyphenidyl
嚴重程度: 中度
Aclidinium and Trihexyphenidyl: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Aclidinium is an inhaled antimuscarinic with low systemic absorption, though some systemic exposure occurs. With trihexyphenidyl, additive anticholinergic effects such as dry mouth, urinary retention, constipation and ocular effects may occur.
用白話說明這項交互作用的意義
Aclidinium and Trihexyphenidyl can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive muscarinic receptor antagonism.
處置方式
Avoid regular concurrent use of other anticholinergics with aclidinium where possible. Monitor for urinary retention, constipation and worsening glaucoma symptoms.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Trihexyphenidyl 的其他交互作用
常見問題
Can I take Aclidinium with Trihexyphenidyl?
MediHelp rates the interaction as moderate. Aclidinium and Trihexyphenidyl can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aclidinium is an inhaled antimuscarinic with low systemic absorption, though some systemic exposure occurs. With trihexyphenidyl, additive anticholinergic effects such as dry mouth, urinary retention, constipation and ocular effects may occur.
How serious is the interaction between Aclidinium and Trihexyphenidyl?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular concurrent use of other anticholinergics with aclidinium where possible. Monitor for urinary retention, constipation and worsening glaucoma symptoms.
What other medicines interact with Trihexyphenidyl?
MediHelp also lists interactions of Trihexyphenidyl with, for example, Orphenadrin, Oxybutynin, Scopolamine. The full list is on the Trihexyphenidyl page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
