藥品參考
Trihexyphenidyl
Trihexyphenidyl is a medicine in the class central nervous system. It is used for parkinson disease.
- 藥物類別: Central Nervous System
- 用途: parkinson disease
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Central Nervous System
- 又稱
- Benzhexol
- 常見規格
- 5 mg, 2 mg
- 已知交互作用
- 89 (嚴重: 5 · 中度: 77 · 輕微: 7)
- 商品名
- 3
- 國家與市場
- 1
用途
作用方式
Trihexyphenidyl inhibits the parasympathetic nervous system and has a relaxing effect on smooth muscles
成人常用劑量（仿單摘要）
Parkinson Disease Initial: 1 mg PO first day, then increase by 2 mg q3-5days until reach 6-10 mg/days
懷孕與哺乳
- 懷孕
- Unknown Limited human data and no animal studies; no clear pattern of birth defects. Near term, anticholinergics given with antipsychotics have caused newborn bowel problems (paralytic ileus). US label: only if clearly needed. Use the lowest dose and tell the delivery team.
- 哺乳
- Unknown Limited data: up to 4 mg daily with haloperidol or risperidone caused no infant effects. LactMed: long-term use might reduce milk production or let-down (less likely with antipsychotics that raise prolactin); watch milk supply and infant weight gain.
已通報的副作用
- Rash
- Anticholinergic side effects
- Suppurative parotitis
- Hallucination
哪些人需要特別留意
- Exacerbation of parkinsonism, neuroleptic malignant syndrome, and withdrawal symptoms results of therapy discontinuation or dose reduction; should be withdrawn gradually
- Use extreme caution and monitor closely patients with liver, cardiac, kidney disorders, prostatic hyperplasia (urinary stricture), or with hypertension
- Drug has atropine-like properties; use with caution in patients with glaucoma, obstructive disease of the gastrointestinal or genitourinary tracts and in elderly males
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (89)
- Orphenadrin + Trihexyphenidyl Major
- Oxybutynin + Trihexyphenidyl Major
- Scopolamine + Trihexyphenidyl Major
- Solifenacin + Trihexyphenidyl Major
- Trihexyphenidyl + Trospium Major
- Abobotulinumtoxina + Trihexyphenidyl Moderate
- Aclidinium + Trihexyphenidyl Moderate
- Amantadine + Trihexyphenidyl Moderate
- Amitriptyline + Trihexyphenidyl Moderate
- Amoxapine + Trihexyphenidyl Moderate
同類別的其他藥品
常見問題
What is Trihexyphenidyl used for?
Trihexyphenidyl is a medicine in the class central nervous system. It is used for Parkinson disease.
What side effects have been reported with Trihexyphenidyl?
Rash, Anticholinergic side effects, Suppurative parotitis, Hallucination.
Can Trihexyphenidyl be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data and no animal studies; no clear pattern of birth defects. Near term, anticholinergics given with antipsychotics have caused newborn bowel problems (paralytic ileus). US label: only if clearly needed. Use the lowest dose and tell the delivery team. Breastfeeding: Unknown. Limited data: up to 4 mg daily with haloperidol or risperidone caused no infant effects. LactMed: long-term use might reduce milk production or let-down (less likely with antipsychotics that raise prolactin); watch milk supply and infant weight gain.
What does Trihexyphenidyl interact with?
MediHelp lists 89 known interactions for Trihexyphenidyl. Major: 5 · Moderate: 77 · Minor: 7. The most serious include Orphenadrin, Oxybutynin, Scopolamine.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
