藥物交互作用
Adalimumab + Denosumab
嚴重程度: 中度
Adalimumab and Denosumab: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Both drugs have been linked to serious infections, and denosumab may contribute to infection risk, notably skin infections, in some patients. Combined with adalimumab's TNF blockade, vigilance for infection is warranted.
用白話說明這項交互作用的意義
Adalimumab and Denosumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Adalimumab belongs to Musculoskeletal; Denosumab belongs to Oncology.
為什麼會發生
Possible additive infection risk; denosumab's RANKL inhibition may modestly affect immune signalling alongside TNF blockade.
處置方式
Monitor for signs of infection, especially skin and urinary infections, and treat early. Reassess denosumab if a serious infection occurs.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Adalimumab 的其他交互作用
- Adalimumab + Bcg vaccine live 禁忌併用
- Adalimumab + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Adalimumab + Measles mumps and rubella vaccine 禁忌併用
- Adalimumab + Measles mumps and rubella vaccine live 禁忌併用
- Adalimumab + Measles mumps rubella and varicella vaccine live 禁忌併用
- Adalimumab + Measles vaccine 禁忌併用
Denosumab 的其他交互作用
常見問題
Can I take Adalimumab with Denosumab?
MediHelp rates the interaction as moderate. Adalimumab and Denosumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have been linked to serious infections, and denosumab may contribute to infection risk, notably skin infections, in some patients. Combined with adalimumab's TNF blockade, vigilance for infection is warranted.
How serious is the interaction between Adalimumab and Denosumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of infection, especially skin and urinary infections, and treat early. Reassess denosumab if a serious infection occurs.
What other medicines interact with Adalimumab?
MediHelp also lists interactions of Adalimumab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Adalimumab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
