藥物交互作用
Anakinra + Denosumab
嚴重程度: 中度
Anakinra and Denosumab: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Anakinra blocks IL-1 and carries a risk of serious infection, and denosumab labeling advises caution with concomitant immunosuppressants. Combined use may further increase infection risk.
用白話說明這項交互作用的意義
Anakinra and Denosumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Anakinra belongs to Musculoskeletal; Denosumab belongs to Oncology.
為什麼會發生
Additive infection risk from IL-1 receptor blockade and RANKL inhibition; no pharmacokinetic mechanism.
處置方式
Monitor for signs of infection and treat early. Interrupt therapy if a serious infection develops.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Anakinra 的其他交互作用
Denosumab 的其他交互作用
常見問題
Can I take Anakinra with Denosumab?
MediHelp rates the interaction as moderate. Anakinra and Denosumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anakinra blocks IL-1 and carries a risk of serious infection, and denosumab labeling advises caution with concomitant immunosuppressants. Combined use may further increase infection risk.
How serious is the interaction between Anakinra and Denosumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of infection and treat early. Interrupt therapy if a serious infection develops.
What other medicines interact with Anakinra?
MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
