藥物交互作用
Alfuzosin + Macimorelin
嚴重程度: 嚴重
Alfuzosin and Macimorelin: major interaction.
最後更新
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摘要
Macimorelin causes a small increase in the QT interval, and alfuzosin may add to this effect. The combination could raise the risk of torsades de pointes during the diagnostic test.
用白話說明這項交互作用的意義
Alfuzosin and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Alfuzosin belongs to Genitourinary; Macimorelin belongs to Endocrine.
為什麼會發生
Additive pharmacodynamic QT prolongation.
處置方式
Withhold alfuzosin for a sufficient washout period before macimorelin testing, or defer the test. Review ECG and electrolytes if both must be given.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Alfuzosin 的其他交互作用
Macimorelin 的其他交互作用
常見問題
Can I take Alfuzosin with Macimorelin?
MediHelp rates the interaction as major. Alfuzosin and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Macimorelin causes a small increase in the QT interval, and alfuzosin may add to this effect. The combination could raise the risk of torsades de pointes during the diagnostic test.
How serious is the interaction between Alfuzosin and Macimorelin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Withhold alfuzosin for a sufficient washout period before macimorelin testing, or defer the test. Review ECG and electrolytes if both must be given.
What other medicines interact with Alfuzosin?
MediHelp also lists interactions of Alfuzosin with, for example, Atazanavir, Cobicistat, Darunavir. The full list is on the Alfuzosin page.
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