藥物交互作用
Amiodarone + Macimorelin
嚴重程度: 嚴重
Amiodarone and Macimorelin: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Macimorelin has a modest QT-prolonging effect and amiodarone is a strong QT-prolonging drug with a very long half-life. Combining them raises the risk of torsades de pointes during the diagnostic test.
用白話說明這項交互作用的意義
Amiodarone and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amiodarone belongs to Cardiovascular; Macimorelin belongs to Endocrine.
為什麼會發生
Additive pharmacodynamic QT prolongation.
處置方式
Avoid macimorelin testing in patients taking amiodarone; use an alternative growth hormone stimulation test. Because amiodarone persists for months, washout is impractical.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Amiodarone 的其他交互作用
Macimorelin 的其他交互作用
常見問題
Can I take Amiodarone with Macimorelin?
MediHelp rates the interaction as major. Amiodarone and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Macimorelin has a modest QT-prolonging effect and amiodarone is a strong QT-prolonging drug with a very long half-life. Combining them raises the risk of torsades de pointes during the diagnostic test.
How serious is the interaction between Amiodarone and Macimorelin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid macimorelin testing in patients taking amiodarone; use an alternative growth hormone stimulation test. Because amiodarone persists for months, washout is impractical.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
