藥物交互作用
Anagrelide + Macimorelin
嚴重程度: 嚴重
Anagrelide and Macimorelin: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
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摘要
Macimorelin can prolong the QT interval, and anagrelide may add to this. The combination could raise the risk of ventricular arrhythmia during or after the diagnostic test.
用白話說明這項交互作用的意義
Anagrelide and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Macimorelin belongs to Endocrine.
為什麼會發生
Additive pharmacodynamic QT prolongation.
處置方式
Avoid using macimorelin in patients taking anagrelide, or use another growth hormone deficiency diagnostic test. If unavoidable, hold anagrelide beforehand where feasible and monitor ECG.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Anagrelide 的其他交互作用
Macimorelin 的其他交互作用
常見問題
Can I take Anagrelide with Macimorelin?
MediHelp rates the interaction as major. Anagrelide and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Macimorelin can prolong the QT interval, and anagrelide may add to this. The combination could raise the risk of ventricular arrhythmia during or after the diagnostic test.
How serious is the interaction between Anagrelide and Macimorelin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using macimorelin in patients taking anagrelide, or use another growth hormone deficiency diagnostic test. If unavoidable, hold anagrelide beforehand where feasible and monitor ECG.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
