藥物交互作用
Almotriptan + Ergotamine
嚴重程度: 禁忌併用
Almotriptan and Ergotamine: contraindicated interaction.
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摘要
Ergotamine and almotriptan both constrict vascular smooth muscle through serotonin receptors. Used in close succession they can cause sustained vasospasm with cerebral or limb ischaemia.
用白話說明這項交互作用的意義
Almotriptan and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Almotriptan belongs to Central Nervous System; Ergotamine belongs to Central Nervous System.
為什麼會發生
Additive vasoconstriction (5-HT1B/1D agonism)
處置方式
Separate the two by at least 24 hours or choose a single agent.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Almotriptan 的其他交互作用
Ergotamine 的其他交互作用
常見問題
Can I take Almotriptan with Ergotamine?
MediHelp rates the interaction as contraindicated. Almotriptan and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and almotriptan both constrict vascular smooth muscle through serotonin receptors. Used in close succession they can cause sustained vasospasm with cerebral or limb ischaemia.
How serious is the interaction between Almotriptan and Ergotamine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate the two by at least 24 hours or choose a single agent.
What other medicines interact with Almotriptan?
MediHelp also lists interactions of Almotriptan with, for example, Dihydroergotamine, Dihydroergotamine intranasal, Eletriptan. The full list is on the Almotriptan page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
