藥物交互作用
Dihydroergotamine + Ergotamine
嚴重程度: 禁忌併用
Dihydroergotamine and Ergotamine: contraindicated interaction.
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摘要
Both are ergot alkaloids with vasoconstrictive actions. Together they can cause additive vasospasm and prolonged ischemia, and labeling advises against use of ergot drugs within a day of each other.
用白話說明這項交互作用的意義
Dihydroergotamine and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dihydroergotamine belongs to Central Nervous System; Ergotamine belongs to Central Nervous System.
為什麼會發生
Additive vasoconstriction from ergot alkaloid agonism at serotonin and adrenergic receptors.
處置方式
Do not use together or within 24 hours of each other. Choose a single ergot agent or a non-ergot alternative.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ergotamine 的其他交互作用
Dihydroergotamine 的其他交互作用
常見問題
Can I take Dihydroergotamine with Ergotamine?
MediHelp rates the interaction as contraindicated. Dihydroergotamine and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both are ergot alkaloids with vasoconstrictive actions. Together they can cause additive vasospasm and prolonged ischemia, and labeling advises against use of ergot drugs within a day of each other.
How serious is the interaction between Dihydroergotamine and Ergotamine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together or within 24 hours of each other. Choose a single ergot agent or a non-ergot alternative.
What other medicines interact with Ergotamine?
MediHelp also lists interactions of Ergotamine with, for example, Almotriptan, Atazanavir, Clarithromycin. The full list is on the Ergotamine page.
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