藥物交互作用
Alogliptin + Chlorpropamide
嚴重程度: 中度
Alogliptin and Chlorpropamide: moderate interaction.
最後更新
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摘要
Alogliptin alone rarely causes hypoglycemia, but with a sulfonylurea such as chlorpropamide the risk increases. Chlorpropamide's long duration can make hypoglycemia prolonged.
用白話說明這項交互作用的意義
Alogliptin and Chlorpropamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin belongs to Endocrine; Chlorpropamide belongs to Endocrine.
為什麼會發生
Additive glucose lowering from DPP-4 inhibition and sulfonylurea-stimulated insulin secretion.
處置方式
Consider reducing the chlorpropamide dose when alogliptin is started and monitor blood glucose for hypoglycemia.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Chlorpropamide 的其他交互作用
Alogliptin 的其他交互作用
常見問題
Can I take Alogliptin with Chlorpropamide?
MediHelp rates the interaction as moderate. Alogliptin and Chlorpropamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alogliptin alone rarely causes hypoglycemia, but with a sulfonylurea such as chlorpropamide the risk increases. Chlorpropamide's long duration can make hypoglycemia prolonged.
How serious is the interaction between Alogliptin and Chlorpropamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider reducing the chlorpropamide dose when alogliptin is started and monitor blood glucose for hypoglycemia.
What other medicines interact with Chlorpropamide?
MediHelp also lists interactions of Chlorpropamide with, for example, Ethanol, Exenatide, Insulin degludec-insulin aspart. The full list is on the Chlorpropamide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
