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藥物交互作用

Aluminum hydroxide + Chenodiol

嚴重程度: 中度

Aluminum hydroxide and Chenodiol: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Aluminum-based antacids can adsorb bile acids, lowering chenodiol absorption and efficacy in gallstone dissolution.

用白話說明這項交互作用的意義

Aluminum hydroxide and Chenodiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Aluminum hydroxide belongs to Gastrointestinal Tract; Chenodiol belongs to Gastrointestinal Tract.

證據等級: Moderate

為什麼會發生

Aluminum hydroxide binds bile acids in the gut, reducing chenodiol absorption.

處置方式

Avoid aluminum-containing antacids or separate by at least 2 hours. Monitor therapeutic response.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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常見問題

Can I take Aluminum hydroxide with Chenodiol?

MediHelp rates the interaction as moderate. Aluminum hydroxide and Chenodiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminum-based antacids can adsorb bile acids, lowering chenodiol absorption and efficacy in gallstone dissolution.

How serious is the interaction between Aluminum hydroxide and Chenodiol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid aluminum-containing antacids or separate by at least 2 hours. Monitor therapeutic response.

What other medicines interact with Aluminum hydroxide?

MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.

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