藥物交互作用
Chenodiol + Colesevelam
嚴重程度: 中度
Chenodiol and Colesevelam: moderate interaction.
最後更新
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摘要
Bile acid sequestrants can bind chenodiol in the gut and reduce its absorption, and they also oppose its effect on bile acid pool. This may reduce gallstone dissolution or therapeutic effect.
用白話說明這項交互作用的意義
Chenodiol and Colesevelam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chenodiol belongs to Gastrointestinal Tract; Colesevelam belongs to Endocrine.
為什麼會發生
Resin binding of bile acids in the gut lowers absorption and enterohepatic availability of chenodiol.
處置方式
Avoid concurrent use if possible; if needed, separate doses by several hours and monitor treatment response.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Colesevelam 的其他交互作用
Chenodiol 的其他交互作用
常見問題
Can I take Chenodiol with Colesevelam?
MediHelp rates the interaction as moderate. Chenodiol and Colesevelam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bile acid sequestrants can bind chenodiol in the gut and reduce its absorption, and they also oppose its effect on bile acid pool. This may reduce gallstone dissolution or therapeutic effect.
How serious is the interaction between Chenodiol and Colesevelam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use if possible; if needed, separate doses by several hours and monitor treatment response.
What other medicines interact with Colesevelam?
MediHelp also lists interactions of Colesevelam with, for example, Amlodipine-olmesartan-hydrochlorothiazide, Amlodipine-olmesartan, Cholic acid. The full list is on the Colesevelam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
