藥物交互作用
Aluminum hydroxide + Ergocalciferol
嚴重程度: 中度
Aluminum hydroxide and Ergocalciferol: moderate interaction.
最後更新
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摘要
Vitamin D increases intestinal absorption of aluminum from aluminum-containing antacids. Chronic use, especially in renal impairment, can cause aluminum accumulation and toxicity affecting bone and the brain.
用白話說明這項交互作用的意義
Aluminum hydroxide and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Ergocalciferol belongs to Musculoskeletal.
為什麼會發生
Vitamin D enhances intestinal absorption of aluminum, and renal impairment limits its excretion.
處置方式
Avoid long-term use of aluminum antacids in patients taking vitamin D, particularly with renal impairment. Use a non-aluminum alternative such as calcium carbonate.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ergocalciferol 的其他交互作用
Aluminum hydroxide 的其他交互作用
常見問題
Can I take Aluminum hydroxide with Ergocalciferol?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Ergocalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vitamin D increases intestinal absorption of aluminum from aluminum-containing antacids. Chronic use, especially in renal impairment, can cause aluminum accumulation and toxicity affecting bone and the brain.
How serious is the interaction between Aluminum hydroxide and Ergocalciferol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid long-term use of aluminum antacids in patients taking vitamin D, particularly with renal impairment. Use a non-aluminum alternative such as calcium carbonate.
What other medicines interact with Ergocalciferol?
MediHelp also lists interactions of Ergocalciferol with, for example, Calcium acetate, Calcium carbonate, Calcium chloride. The full list is on the Ergocalciferol page.
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