藥物交互作用
Amikacin + Cefaclor
嚴重程度: 輕微
Amikacin and Cefaclor: minor interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Cefaclor given with amikacin may add to the risk of kidney injury, particularly in patients with renal impairment or volume depletion. Amikacin is the principal nephrotoxic and ototoxic drug, and reduced renal function increases its exposure. Oral cefaclor is only weakly nephrotoxic.
用白話說明這項交互作用的意義
Amikacin and Cefaclor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amikacin belongs to Anti Bacterial; Cefaclor belongs to Anti Bacterial.
為什麼會發生
Possible additive nephrotoxic potential; evidence for cefaclor is weak.
處置方式
Monitor serum creatinine and amikacin levels during therapy. Adjust the amikacin dose for renal function.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Cefaclor 的其他交互作用
Amikacin 的其他交互作用
常見問題
Can I take Amikacin with Cefaclor?
MediHelp rates the interaction as minor. Amikacin and Cefaclor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefaclor given with amikacin may add to the risk of kidney injury, particularly in patients with renal impairment or volume depletion. Amikacin is the principal nephrotoxic and ototoxic drug, and reduced renal function increases its exposure. Oral cefaclor is only weakly nephrotoxic.
How serious is the interaction between Amikacin and Cefaclor?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and amikacin levels during therapy. Adjust the amikacin dose for renal function.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
