藥物交互作用
Amikacin + Cefuroxime
嚴重程度: 中度
Amikacin and Cefuroxime: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Cefuroxime given with amikacin may increase the risk of kidney injury, especially in older, dehydrated or renally impaired patients. Amikacin is the principal nephrotoxic and ototoxic agent, and the combination is often used on purpose in serious infections.
用白話說明這項交互作用的意義
Amikacin and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amikacin belongs to Anti Bacterial; Cefuroxime belongs to Anti Bacterial.
為什麼會發生
Additive nephrotoxic potential; cephalosporins may modestly add to aminoglycoside tubular injury.
處置方式
Monitor serum creatinine and amikacin levels, keep the patient hydrated and limit the aminoglycoside duration. Adjust the doses for renal function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefuroxime 的其他交互作用
Amikacin 的其他交互作用
常見問題
Can I take Amikacin with Cefuroxime?
MediHelp rates the interaction as moderate. Amikacin and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefuroxime given with amikacin may increase the risk of kidney injury, especially in older, dehydrated or renally impaired patients. Amikacin is the principal nephrotoxic and ototoxic agent, and the combination is often used on purpose in serious infections.
How serious is the interaction between Amikacin and Cefuroxime?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and amikacin levels, keep the patient hydrated and limit the aminoglycoside duration. Adjust the doses for renal function.
What other medicines interact with Cefuroxime?
MediHelp also lists interactions of Cefuroxime with, for example, Aluminum hydroxide, Bcg vaccine live, Calcium carbonate. The full list is on the Cefuroxime page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
