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藥物交互作用

Calcium + Cefuroxime

嚴重程度: 中度

Calcium and Cefuroxime: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Cefuroxime axetil absorption may be reduced when gastric pH is raised by antacids, including calcium carbonate. This can lower antibiotic exposure.

用白話說明這項交互作用的意義

Calcium and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Calcium belongs to Gastrointestinal Tract; Cefuroxime belongs to Anti Bacterial.

證據等級: Moderate

為什麼會發生

Raised gastric pH impairs dissolution and absorption of cefuroxime axetil.

處置方式

Give cefuroxime axetil with food and separate it from calcium carbonate by about 2 hours.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Calcium with Cefuroxime?

MediHelp rates the interaction as moderate. Calcium and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefuroxime axetil absorption may be reduced when gastric pH is raised by antacids, including calcium carbonate. This can lower antibiotic exposure.

How serious is the interaction between Calcium and Cefuroxime?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give cefuroxime axetil with food and separate it from calcium carbonate by about 2 hours.

What other medicines interact with Calcium?

MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.

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