藥物交互作用
Aluminum hydroxide + Cefuroxime
嚴重程度: 中度
Aluminum hydroxide and Cefuroxime: moderate interaction.
最後更新
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摘要
Raising gastric pH with antacids lowers the bioavailability of oral cefuroxime axetil. Reduced exposure may cause treatment failure in infections.
用白話說明這項交互作用的意義
Aluminum hydroxide and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Cefuroxime belongs to Anti Bacterial.
為什麼會發生
Elevated gastric pH reduces dissolution and absorption of cefuroxime axetil.
處置方式
Separate cefuroxime axetil from the antacid by at least 2 hours, giving cefuroxime with food. Monitor clinical response if acid-reducing therapy is continuous.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Aluminum hydroxide 的其他交互作用
Cefuroxime 的其他交互作用
常見問題
Can I take Aluminum hydroxide with Cefuroxime?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Raising gastric pH with antacids lowers the bioavailability of oral cefuroxime axetil. Reduced exposure may cause treatment failure in infections.
How serious is the interaction between Aluminum hydroxide and Cefuroxime?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate cefuroxime axetil from the antacid by at least 2 hours, giving cefuroxime with food. Monitor clinical response if acid-reducing therapy is continuous.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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