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藥物交互作用

Aminolevulinic acid + Amlodipine-olmesartan-hydrochlorothiazide

嚴重程度: 中度

Aminolevulinic acid and Amlodipine-olmesartan-hydrochlorothiazide: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Hydrochlorothiazide is a photosensitizing drug, and oral aminolevulinic acid causes photosensitivity used for imaging during surgery. Together they may increase the risk of phototoxic skin reactions.

用白話說明這項交互作用的意義

Aminolevulinic acid and Amlodipine-olmesartan-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Aminolevulinic acid belongs to Miscellaneous; Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular.

證據等級: Low

為什麼會發生

Additive phototoxicity from two photosensitizing agents.

處置方式

Avoid other photosensitizing drugs during the perioperative period of aminolevulinic acid use, and counsel on strict sun and bright light protection. Hold hydrochlorothiazide temporarily if clinically appropriate.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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常見問題

Can I take Aminolevulinic acid with Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp rates the interaction as moderate. Aminolevulinic acid and Amlodipine-olmesartan-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydrochlorothiazide is a photosensitizing drug, and oral aminolevulinic acid causes photosensitivity used for imaging during surgery. Together they may increase the risk of phototoxic skin reactions.

How serious is the interaction between Aminolevulinic acid and Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid other photosensitizing drugs during the perioperative period of aminolevulinic acid use, and counsel on strict sun and bright light protection. Hold hydrochlorothiazide temporarily if clinically appropriate.

What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.

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