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Amobarbital + Levothyroxine

嚴重程度: 中度

Amobarbital and Levothyroxine: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Barbiturates can speed up levothyroxine metabolism, which may raise dose requirements and lead to hypothyroidism in treated patients.

用白話說明這項交互作用的意義

Amobarbital and Levothyroxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amobarbital belongs to Central Nervous System; Levothyroxine belongs to Endocrine.

證據等級: Moderate

為什麼會發生

Hepatic enzyme induction increases levothyroxine clearance.

處置方式

Check TSH after starting or stopping amobarbital, and adjust the levothyroxine dose accordingly.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用，即可解鎖 Amobarbital 與 Levothyroxine 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
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常見問題

Can I take Amobarbital with Levothyroxine?

MediHelp rates the interaction as moderate. Amobarbital and Levothyroxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Barbiturates can speed up levothyroxine metabolism, which may raise dose requirements and lead to hypothyroidism in treated patients.

How serious is the interaction between Amobarbital and Levothyroxine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check TSH after starting or stopping amobarbital, and adjust the levothyroxine dose accordingly.

What other medicines interact with Amobarbital?

MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.

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