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藥物交互作用

Amoxapine + Dicyclomine

嚴重程度: 中度

Amoxapine and Dicyclomine: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Amoxapine has anticholinergic properties, which add to those of dicyclomine. The combination may cause marked dry mouth, constipation, urinary retention, blurred vision, confusion and tachycardia, particularly in older people.

用白話說明這項交互作用的意義

Amoxapine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

證據等級: Moderate

為什麼會發生

Additive muscarinic receptor blockade.

處置方式

Monitor for anticholinergic toxicity and consider a lower dicyclomine dose or a less anticholinergic alternative. Take extra care in older patients and those with glaucoma or urinary obstruction.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
  • Evidence detail
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常見問題

Can I take Amoxapine with Dicyclomine?

MediHelp rates the interaction as moderate. Amoxapine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amoxapine has anticholinergic properties, which add to those of dicyclomine. The combination may cause marked dry mouth, constipation, urinary retention, blurred vision, confusion and tachycardia, particularly in older people.

How serious is the interaction between Amoxapine and Dicyclomine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic toxicity and consider a lower dicyclomine dose or a less anticholinergic alternative. Take extra care in older patients and those with glaucoma or urinary obstruction.

What other medicines interact with Dicyclomine?

MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.

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