藥物交互作用
Anagrelide + Loperamide
嚴重程度: 嚴重
Anagrelide and Loperamide: major interaction.
最後更新
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摘要
Both agents can prolong the QT interval, so combining them raises the risk of ventricular arrhythmia including torsades de pointes. The risk rises with high loperamide doses.
用白話說明這項交互作用的意義
Anagrelide and Loperamide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Loperamide belongs to Gastrointestinal Tract.
為什麼會發生
Additive QT prolongation through cardiac ion channel effects.
處置方式
Avoid if possible and do not exceed labeled loperamide doses. Monitor ECG and correct electrolyte abnormalities.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Loperamide 的其他交互作用
Anagrelide 的其他交互作用
常見問題
Can I take Anagrelide with Loperamide?
MediHelp rates the interaction as major. Anagrelide and Loperamide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both agents can prolong the QT interval, so combining them raises the risk of ventricular arrhythmia including torsades de pointes. The risk rises with high loperamide doses.
How serious is the interaction between Anagrelide and Loperamide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible and do not exceed labeled loperamide doses. Monitor ECG and correct electrolyte abnormalities.
What other medicines interact with Loperamide?
MediHelp also lists interactions of Loperamide with, for example, Amiodarone, Amisulpride, Artemether / lumefantrine. The full list is on the Loperamide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
