藥物交互作用
Anagrelide + Ofloxacin
嚴重程度: 嚴重
Anagrelide and Ofloxacin: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Anagrelide can prolong the QT interval and cause tachyarrhythmias, and ofloxacin may add to the QT effect. Together they may increase the risk of serious ventricular arrhythmia.
用白話說明這項交互作用的意義
Anagrelide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Ofloxacin belongs to Anti Bacterial.
為什麼會發生
Additive QT prolongation.
處置方式
Avoid the combination when an alternative antibiotic exists. If needed, check baseline ECG and electrolytes and monitor the QTc.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ofloxacin 的其他交互作用
Anagrelide 的其他交互作用
常見問題
Can I take Anagrelide with Ofloxacin?
MediHelp rates the interaction as major. Anagrelide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Anagrelide can prolong the QT interval and cause tachyarrhythmias, and ofloxacin may add to the QT effect. Together they may increase the risk of serious ventricular arrhythmia.
How serious is the interaction between Anagrelide and Ofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination when an alternative antibiotic exists. If needed, check baseline ECG and electrolytes and monitor the QTc.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。