藥物交互作用
Amisulpride + Ofloxacin
嚴重程度: 嚴重
Amisulpride and Ofloxacin: major interaction.
最後更新
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摘要
Amisulpride causes dose-related QT prolongation and ofloxacin may add to this effect, increasing the chance of torsades de pointes. Patients with electrolyte disturbances or heart disease are at particular risk.
用白話說明這項交互作用的意義
Amisulpride and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Ofloxacin belongs to Anti Bacterial.
為什麼會發生
Additive QT prolongation through effects on cardiac repolarization.
處置方式
Prefer an alternative antibiotic. If coadministered, perform ECG monitoring and correct potassium and magnesium.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ofloxacin 的其他交互作用
Amisulpride 的其他交互作用
常見問題
Can I take Amisulpride with Ofloxacin?
MediHelp rates the interaction as major. Amisulpride and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amisulpride causes dose-related QT prolongation and ofloxacin may add to this effect, increasing the chance of torsades de pointes. Patients with electrolyte disturbances or heart disease are at particular risk.
How serious is the interaction between Amisulpride and Ofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer an alternative antibiotic. If coadministered, perform ECG monitoring and correct potassium and magnesium.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
