藥物交互作用
Anti-thymocyte + Ciltacabtagene autoleucel
嚴重程度: 嚴重
Anti-thymocyte and Ciltacabtagene autoleucel: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Antithymocyte globulin depletes T cells and can eliminate infused CAR T cells, reducing efficacy while adding to immunosuppression and infection risk.
用白話說明這項交互作用的意義
Anti-thymocyte and Ciltacabtagene autoleucel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anti-thymocyte belongs to Miscellaneous; Ciltacabtagene autoleucel belongs to Miscellaneous.
為什麼會發生
Lympholytic activity of ATG eliminates CAR T cells and adds immunosuppression.
處置方式
Avoid ATG around CAR T infusion unless required for life-threatening toxicity. Monitor for infection and CAR T persistence.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Anti-thymocyte 的其他交互作用
- Anti-thymocyte + Bcg vaccine live 禁忌併用
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Anti-thymocyte + Measles mumps and rubella vaccine live 禁忌併用
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live 禁忌併用
- Anti-thymocyte + Measles vaccine 禁忌併用
- Anti-thymocyte + Rotavirus oral vaccine live 禁忌併用
Ciltacabtagene autoleucel 的其他交互作用
常見問題
Can I take Anti-thymocyte with Ciltacabtagene autoleucel?
MediHelp rates the interaction as major. Anti-thymocyte and Ciltacabtagene autoleucel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antithymocyte globulin depletes T cells and can eliminate infused CAR T cells, reducing efficacy while adding to immunosuppression and infection risk.
How serious is the interaction between Anti-thymocyte and Ciltacabtagene autoleucel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ATG around CAR T infusion unless required for life-threatening toxicity. Monitor for infection and CAR T persistence.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
