藥物交互作用
Anti-thymocyte + Ponesimod
嚴重程度: 嚴重
Anti-thymocyte and Ponesimod: major interaction.
最後更新
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摘要
Anti-thymocyte globulin causes profound lymphocyte depletion and ponesimod reduces circulating lymphocytes by sequestration. Combined, they may substantially raise the risk of serious infection, and effects persist after either drug is stopped.
用白話說明這項交互作用的意義
Anti-thymocyte and Ponesimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anti-thymocyte belongs to Miscellaneous; Ponesimod belongs to Central Nervous System.
為什麼會發生
Additive immunosuppression via T-cell depletion and S1P receptor modulation.
處置方式
Avoid starting ponesimod during or soon after anti-thymocyte globulin where possible. If used, monitor lymphocyte counts and infection signs closely.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Anti-thymocyte 的其他交互作用
- Anti-thymocyte + Bcg vaccine live 禁忌併用
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Anti-thymocyte + Measles mumps and rubella vaccine live 禁忌併用
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live 禁忌併用
- Anti-thymocyte + Measles vaccine 禁忌併用
- Anti-thymocyte + Rotavirus oral vaccine live 禁忌併用
Ponesimod 的其他交互作用
常見問題
Can I take Anti-thymocyte with Ponesimod?
MediHelp rates the interaction as major. Anti-thymocyte and Ponesimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Anti-thymocyte globulin causes profound lymphocyte depletion and ponesimod reduces circulating lymphocytes by sequestration. Combined, they may substantially raise the risk of serious infection, and effects persist after either drug is stopped.
How serious is the interaction between Anti-thymocyte and Ponesimod?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid starting ponesimod during or soon after anti-thymocyte globulin where possible. If used, monitor lymphocyte counts and infection signs closely.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
