藥物交互作用
Antithrombin iii + Bazedoxifene-conjugated estrogens
嚴重程度: 嚴重
Antithrombin iii and Bazedoxifene-conjugated estrogens: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Antithrombin III is given to patients with a thrombotic tendency from antithrombin deficiency. Estrogen-containing therapy increases clotting risk and may offset anticoagulant protection.
用白話說明這項交互作用的意義
Antithrombin iii and Bazedoxifene-conjugated estrogens can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Estrogens increase procoagulant factors and venous thrombosis risk, opposing antithrombin's anticoagulant effect.
處置方式
Avoid the estrogen-bazedoxifene product in patients needing antithrombin therapy. Use non-hormonal options for menopausal symptoms.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Bazedoxifene-conjugated estrogens 的其他交互作用
- Anastrozole + Bazedoxifene-conjugated estrogens 禁忌併用
- Bazedoxifene-conjugated estrogens + Ospemifene 禁忌併用
- Antithrombin alfa + Bazedoxifene-conjugated estrogens 嚴重
- Bazedoxifene-conjugated estrogens + Bemiparin 嚴重
- Bazedoxifene-conjugated estrogens + Carbamazepine 嚴重
- Bazedoxifene-conjugated estrogens + Dalteparin 嚴重
常見問題
Can I take Antithrombin iii with Bazedoxifene-conjugated estrogens?
MediHelp rates the interaction as major. Antithrombin iii and Bazedoxifene-conjugated estrogens can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antithrombin III is given to patients with a thrombotic tendency from antithrombin deficiency. Estrogen-containing therapy increases clotting risk and may offset anticoagulant protection.
How serious is the interaction between Antithrombin iii and Bazedoxifene-conjugated estrogens?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the estrogen-bazedoxifene product in patients needing antithrombin therapy. Use non-hormonal options for menopausal symptoms.
What other medicines interact with Bazedoxifene-conjugated estrogens?
MediHelp also lists interactions of Bazedoxifene-conjugated estrogens with, for example, Anastrozole, Ospemifene, Antithrombin alfa. The full list is on the Bazedoxifene-conjugated estrogens page.
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