藥物交互作用
Bazedoxifene-conjugated estrogens + Ospemifene
嚴重程度: 禁忌併用
Bazedoxifene-conjugated estrogens and Ospemifene: contraindicated interaction.
最後更新
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摘要
Both are estrogen agonist/antagonist agents with estrogenic effects on the endometrium and venous thromboembolism risk. Combining them adds duplicate therapy and additive risk of thromboembolic events and endometrial effects without benefit.
用白話說明這項交互作用的意義
Bazedoxifene-conjugated estrogens and Ospemifene are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Bazedoxifene-conjugated estrogens belongs to Endocrine; Ospemifene belongs to Endocrine.
為什麼會發生
Additive pharmacodynamic estrogen-receptor modulation with duplicated prothrombotic and endometrial effects.
處置方式
Do not use together; choose one agent for menopausal symptoms.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Bazedoxifene-conjugated estrogens 的其他交互作用
- Anastrozole + Bazedoxifene-conjugated estrogens 禁忌併用
- Antithrombin alfa + Bazedoxifene-conjugated estrogens 嚴重
- Antithrombin iii + Bazedoxifene-conjugated estrogens 嚴重
- Bazedoxifene-conjugated estrogens + Bemiparin 嚴重
- Bazedoxifene-conjugated estrogens + Carbamazepine 嚴重
- Bazedoxifene-conjugated estrogens + Dalteparin 嚴重
Ospemifene 的其他交互作用
常見問題
Can I take Bazedoxifene-conjugated estrogens with Ospemifene?
MediHelp rates the interaction as contraindicated. Bazedoxifene-conjugated estrogens and Ospemifene are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both are estrogen agonist/antagonist agents with estrogenic effects on the endometrium and venous thromboembolism risk. Combining them adds duplicate therapy and additive risk of thromboembolic events and endometrial effects without benefit.
How serious is the interaction between Bazedoxifene-conjugated estrogens and Ospemifene?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose one agent for menopausal symptoms.
What other medicines interact with Bazedoxifene-conjugated estrogens?
MediHelp also lists interactions of Bazedoxifene-conjugated estrogens with, for example, Anastrozole, Antithrombin alfa, Antithrombin iii. The full list is on the Bazedoxifene-conjugated estrogens page.
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