藥物交互作用
Antithymocyte globulin equine + Human papillomavirus vaccine
嚴重程度: 中度
Antithymocyte globulin equine and Human papillomavirus vaccine: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Equine antithymocyte globulin depletes T lymphocytes and causes profound immunosuppression, which can blunt the antibody response to HPV vaccination. Vaccine-induced protection may therefore be incomplete or short-lived.
用白話說明這項交互作用的意義
Antithymocyte globulin equine and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
T-cell depletion by the antithymocyte globulin impairs the immune response to the inactivated vaccine.
處置方式
Give HPV vaccine before starting antithymocyte globulin when feasible. If vaccinated during or soon after treatment, consider revaccination or antibody assessment once immune recovery has occurred.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Human papillomavirus vaccine 的其他交互作用
- Antithymocyte globulin rabbit + Human papillomavirus vaccine 中度
- Atidarsagene autotemcel + Human papillomavirus vaccine 中度
- Belimumab + Human papillomavirus vaccine 中度
- Cortisone + Human papillomavirus vaccine 中度
- Cyclosporine + Human papillomavirus vaccine 中度
- Elivaldogene autotemcel + Human papillomavirus vaccine 中度
常見問題
Can I take Antithymocyte globulin equine with Human papillomavirus vaccine?
MediHelp rates the interaction as moderate. Antithymocyte globulin equine and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Equine antithymocyte globulin depletes T lymphocytes and causes profound immunosuppression, which can blunt the antibody response to HPV vaccination. Vaccine-induced protection may therefore be incomplete or short-lived.
How serious is the interaction between Antithymocyte globulin equine and Human papillomavirus vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give HPV vaccine before starting antithymocyte globulin when feasible. If vaccinated during or soon after treatment, consider revaccination or antibody assessment once immune recovery has occurred.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin rabbit, Atidarsagene autotemcel, Belimumab. The full list is on the Human papillomavirus vaccine page.
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