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藥物交互作用

Elivaldogene autotemcel + Human papillomavirus vaccine

嚴重程度: 中度

Elivaldogene autotemcel and Human papillomavirus vaccine: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Vaccine safety and efficacy during or after elivaldogene autotemcel have not been studied. Myeloablative conditioning and subsequent immune reconstitution are expected to impair vaccine responses.

用白話說明這項交互作用的意義

Elivaldogene autotemcel and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

證據等級: Low

為什麼會發生

Myeloablative conditioning and hematopoietic reconstitution impair vaccine responses.

處置方式

Vaccinate at least 6 weeks before myeloablative conditioning where feasible. Defer vaccination until hematologic recovery, then revaccinate per guidelines.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Elivaldogene autotemcel with Human papillomavirus vaccine?

MediHelp rates the interaction as moderate. Elivaldogene autotemcel and Human papillomavirus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vaccine safety and efficacy during or after elivaldogene autotemcel have not been studied. Myeloablative conditioning and subsequent immune reconstitution are expected to impair vaccine responses.

How serious is the interaction between Elivaldogene autotemcel and Human papillomavirus vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate at least 6 weeks before myeloablative conditioning where feasible. Defer vaccination until hematologic recovery, then revaccinate per guidelines.

What other medicines interact with Human papillomavirus vaccine?

MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.

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