藥物交互作用
Asenapine + Pasireotide
嚴重程度: 嚴重
Asenapine and Pasireotide: major interaction.
最後更新
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摘要
Both drugs can prolong the QT interval, and pasireotide also causes bradycardia. Combined use raises the risk of torsades de pointes.
用白話說明這項交互作用的意義
Asenapine and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Asenapine belongs to Central Nervous System; Pasireotide belongs to Endocrine.
為什麼會發生
Additive QTc prolongation, with bradycardia from pasireotide.
處置方式
Obtain a baseline ECG and monitor it periodically. Correct hypokalemia and hypomagnesemia before and during therapy.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Asenapine 的其他交互作用
Pasireotide 的其他交互作用
常見問題
Can I take Asenapine with Pasireotide?
MediHelp rates the interaction as major. Asenapine and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can prolong the QT interval, and pasireotide also causes bradycardia. Combined use raises the risk of torsades de pointes.
How serious is the interaction between Asenapine and Pasireotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor it periodically. Correct hypokalemia and hypomagnesemia before and during therapy.
What other medicines interact with Asenapine?
MediHelp also lists interactions of Asenapine with, for example, Pimozide, Thioridazine, Vandetanib. The full list is on the Asenapine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
