藥物交互作用
Anagrelide + Pasireotide
嚴重程度: 嚴重
Anagrelide and Pasireotide: major interaction.
最後更新
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摘要
Pasireotide can prolong the QT interval and slow the heart rate, and anagrelide may add to the QT effect. Combined use increases the risk of ventricular arrhythmia.
用白話說明這項交互作用的意義
Anagrelide and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Pasireotide belongs to Endocrine.
為什麼會發生
Additive pharmacodynamic QT prolongation, with bradycardia from pasireotide as an additional risk.
處置方式
Avoid if possible. If co-use is needed, check ECG at baseline and during therapy and correct potassium and magnesium.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Anagrelide 的其他交互作用
Pasireotide 的其他交互作用
常見問題
Can I take Anagrelide with Pasireotide?
MediHelp rates the interaction as major. Anagrelide and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pasireotide can prolong the QT interval and slow the heart rate, and anagrelide may add to the QT effect. Combined use increases the risk of ventricular arrhythmia.
How serious is the interaction between Anagrelide and Pasireotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible. If co-use is needed, check ECG at baseline and during therapy and correct potassium and magnesium.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
