藥物交互作用
Amisulpride + Pasireotide
嚴重程度: 嚴重
Amisulpride and Pasireotide: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Pasireotide can prolong the QT interval and cause bradycardia, and amisulpride also prolongs QT. Together they may increase the risk of ventricular arrhythmias.
用白話說明這項交互作用的意義
Amisulpride and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Pasireotide belongs to Endocrine.
為什麼會發生
Additive QT prolongation, with pasireotide-related bradycardia and hypokalemia adding risk.
處置方式
Obtain a baseline ECG and monitor it during treatment, correcting potassium and magnesium. Use an alternative to amisulpride when feasible.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Amisulpride 的其他交互作用
Pasireotide 的其他交互作用
常見問題
Can I take Amisulpride with Pasireotide?
MediHelp rates the interaction as major. Amisulpride and Pasireotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pasireotide can prolong the QT interval and cause bradycardia, and amisulpride also prolongs QT. Together they may increase the risk of ventricular arrhythmias.
How serious is the interaction between Amisulpride and Pasireotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor it during treatment, correcting potassium and magnesium. Use an alternative to amisulpride when feasible.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
