藥物交互作用
Atazanavir + Dronabinol
嚴重程度: 中度
Atazanavir and Dronabinol: moderate interaction.
最後更新
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摘要
Atazanavir inhibits CYP3A4 and may raise dronabinol concentrations. This can increase psychoactive and cardiovascular effects such as tachycardia, dizziness, anxiety and sedation.
用白話說明這項交互作用的意義
Atazanavir and Dronabinol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atazanavir belongs to Anti Virals; Dronabinol belongs to Central Nervous System.
為什麼會發生
Inhibition of CYP3A4-mediated dronabinol metabolism.
處置方式
Monitor for excessive CNS effects, tachycardia and hypotension, and lower the dronabinol dose if these occur.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Dronabinol 的其他交互作用
Atazanavir 的其他交互作用
常見問題
Can I take Atazanavir with Dronabinol?
MediHelp rates the interaction as moderate. Atazanavir and Dronabinol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atazanavir inhibits CYP3A4 and may raise dronabinol concentrations. This can increase psychoactive and cardiovascular effects such as tachycardia, dizziness, anxiety and sedation.
How serious is the interaction between Atazanavir and Dronabinol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive CNS effects, tachycardia and hypotension, and lower the dronabinol dose if these occur.
What other medicines interact with Dronabinol?
MediHelp also lists interactions of Dronabinol with, for example, Cefotetan, Disulfiram, Midazolam intranasal. The full list is on the Dronabinol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
