藥物交互作用
Cefotetan + Dronabinol
嚴重程度: 禁忌併用
Cefotetan and Dronabinol: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Dronabinol oral solution contains a large amount of ethanol, and cefotetan can cause disulfiram-like reactions with alcohol. Flushing, nausea, vomiting, tachycardia and hypotension may result.
用白話說明這項交互作用的意義
Cefotetan and Dronabinol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cefotetan belongs to Anti Bacterial; Dronabinol belongs to Central Nervous System.
為什麼會發生
Cefotetan inhibits aldehyde dehydrogenase, causing acetaldehyde accumulation from the ethanol in the dronabinol solution.
處置方式
Do not use dronabinol oral solution with cefotetan or within several days of either drug. Use dronabinol capsules or another antiemetic if cefotetan is needed.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Dronabinol 的其他交互作用
Cefotetan 的其他交互作用
常見問題
Can I take Cefotetan with Dronabinol?
MediHelp rates the interaction as contraindicated. Cefotetan and Dronabinol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Dronabinol oral solution contains a large amount of ethanol, and cefotetan can cause disulfiram-like reactions with alcohol. Flushing, nausea, vomiting, tachycardia and hypotension may result.
How serious is the interaction between Cefotetan and Dronabinol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use dronabinol oral solution with cefotetan or within several days of either drug. Use dronabinol capsules or another antiemetic if cefotetan is needed.
What other medicines interact with Dronabinol?
MediHelp also lists interactions of Dronabinol with, for example, Disulfiram, Midazolam intranasal, Zuranolone. The full list is on the Dronabinol page.
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