藥物交互作用
Atezolizumab + Cefalexin
嚴重程度: 輕微
Atezolizumab and Cefalexin: minor interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Observational data link antibiotic exposure around the start of immune checkpoint inhibitor therapy with poorer outcomes, possibly through gut microbiome disruption. The evidence is associative and confounded by patient illness severity. The effect on any individual patient is uncertain.
用白話說明這項交互作用的意義
Atezolizumab and Cefalexin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atezolizumab belongs to Oncology; Cefalexin belongs to Anti Bacterial.
為什麼會發生
Proposed disruption of gut microbiota that may modulate antitumor immune response; not firmly established.
處置方式
Prescribe the antibiotic only when clearly indicated and keep the course short. Do not withhold needed antibiotics.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Cefalexin 的其他交互作用
Atezolizumab 的其他交互作用
常見問題
Can I take Atezolizumab with Cefalexin?
MediHelp rates the interaction as minor. Atezolizumab and Cefalexin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Observational data link antibiotic exposure around the start of immune checkpoint inhibitor therapy with poorer outcomes, possibly through gut microbiome disruption. The evidence is associative and confounded by patient illness severity. The effect on any individual patient is uncertain.
How serious is the interaction between Atezolizumab and Cefalexin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prescribe the antibiotic only when clearly indicated and keep the course short. Do not withhold needed antibiotics.
What other medicines interact with Cefalexin?
MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。